Praziquantel: Treatment of Worm Infections and Schistosoma Infections
Praziquantel is a widely used anthelmintic medication effective against various parasitic worm infections, including schistosomiasis and tapeworm infections. It works by increasing the permeability of the parasite’s cell membrane to calcium ions, leading to paralysis and death of the parasite, which is then eliminated by the host’s immune system. Medzsupplier is Top Praziquantel Tablet Wholesaler, supplier and exporter. Buy Praziquantel Online at Medzsupplier.
Schistosoma Infections
Schistosomiasis, caused by Schistosoma species, is a serious parasitic disease affecting millions worldwide. The infection occurs when larvae, present in contaminated water, penetrate human skin. Symptoms include fever, abdominal pain, and blood in urine or stool. Praziquantel is the preferred treatment, effectively eliminating adult worms and reducing complications such as liver fibrosis and bladder damage. A single or divided dose is usually sufficient to clear the infection.
Other Worm Infections
Praziquantel is also effective against tapeworms, including Taenia solium (pork tapeworm) and Diphyllobothrium latum (fish tapeworm). In cases of neurocysticercosis, caused by larval tapeworms in the brain, Praziquantel is sometimes used alongside corticosteroids to manage inflammation.
Dosage and Safety
The dosage depends on the infection type, with a common regimen of 10–40 mg/kg administered in single or multiple doses. Side effects are generally mild, including headache, dizziness, and nausea. Praziquantel is not recommended for pregnant women in the first trimester and should be used with caution in those with severe liver disease.
Overall, Praziquantel remains a crucial drug in the fight against parasitic infections, providing effective treatment for millions worldwide.
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