How Long Does It Take for Isotretinoin to Work?

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How Long Does It Take for Isotretinoin to Work?

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Isotretinoin 20mg, a powerful oral medication for severe acne, does not produce immediate results.... View more

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Isotretinoin 20mg, a powerful oral medication for severe acne, does not produce immediate results. Most patients begin noticing improvement after 4 to 6 weeks of consistent use. However, acne may actually worsen during the first few weeks, a phase known as the “initial flare-up.” This happens as the medication pushes out impurities and reduces oil gland activity.

Significant clearing of acne typically occurs within 3 to 4 months, though some people may require a longer course, lasting up to 6 to 8 months, depending on severity and dosage. By shrinking oil glands, reducing bacteria, and preventing clogged pores, isotretinoin delivers long-lasting remission in many patients.

Patience is key—while the early stages can be discouraging, the results are often transformative. Regular follow-ups with a dermatologist ensure proper monitoring, dosage adjustments, and management of side effects, making isotretinoin one of the most effective treatments for persistent acne.

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